Cholestasis and Acute Cholecystitis in Hyperthyroidism Treated With Methimazole
Accepted 11 March 2009.
Summary
Hepatic dysfunction and jaundice are usually present in patients with hyperthyroidism. It may be the clinical manifestation of the disease or the adverse effect of antithyroid therapy. We report a 69-year-old male with hyperthyroidism who developed cholestasis and acute cholecystitis after a 4-day course of methimazole. After withdrawal of methimazole, his cholestasis subsided.
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aDivision of Endocrinology and Metabolism, Department of Internal Medicine, Taipei, Taiwan
bDivision of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan
cMackay Medicine, Nursing and Management College, Taipei, Taiwan
Correspondence to: Dr Wei-Che Chen, Division of Endocrinology and Metabolism, Department of Internal Medicine, Mackay Memorial Hospital, 92, Section 2, Chung-Shan North Road, Taipei, Taiwan
ABSTRACT