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Volume 3, Issue 4, Pages 248-250 (December 2009)


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Cholestasis and Acute Cholecystitis in Hyperthyroidism Treated With Methimazole

Wei-Che ChenaCorresponding Author Informationemail address, Zheng-Xin Zhubc, Chao-Hung Wanga, Ming-Nan Chienac

Accepted 11 March 2009.

Summary 

Hepatic dysfunction and jaundice are usually present in patients with hyperthyroidism. It may be the clinical manifestation of the disease or the adverse effect of antithyroid therapy. We report a 69-year-old male with hyperthyroidism who developed cholestasis and acute cholecystitis after a 4-day course of methimazole. After withdrawal of methimazole, his cholestasis subsided.

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a Division of Endocrinology and Metabolism, Department of Internal Medicine, Taipei, Taiwan

b Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan

c Mackay Medicine, Nursing and Management College, Taipei, Taiwan

Corresponding Author InformationCorrespondence to: Dr Wei-Che Chen, Division of Endocrinology and Metabolism, Department of Internal Medicine, Mackay Memorial Hospital, 92, Section 2, Chung-Shan North Road, Taipei, Taiwan

PII: S1873-9598(10)70009-0

doi:10.1016/S1873-9598(10)70009-0


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