International Journal of Gerontology
Volume 3, Issue 4 , Pages 248-250, December 2009

Cholestasis and Acute Cholecystitis in Hyperthyroidism Treated With Methimazole

  • Wei-Che Chen

      Affiliations

    • Division of Endocrinology and Metabolism, Department of Internal Medicine, Taipei, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Wei-Che Chen, Division of Endocrinology and Metabolism, Department of Internal Medicine, Mackay Memorial Hospital, 92, Section 2, Chung-Shan North Road, Taipei, Taiwan
    • ,
  • Zheng-Xin Zhu

      Affiliations

    • Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan
    • Mackay Medicine, Nursing and Management College, Taipei, Taiwan
    • ,
  • Chao-Hung Wang

      Affiliations

    • Division of Endocrinology and Metabolism, Department of Internal Medicine, Taipei, Taiwan
    • ,
  • Ming-Nan Chien

      Affiliations

    • Division of Endocrinology and Metabolism, Department of Internal Medicine, Taipei, Taiwan
    • Mackay Medicine, Nursing and Management College, Taipei, Taiwan

Accepted 11 March 2009.

Summary 

Hepatic dysfunction and jaundice are usually present in patients with hyperthyroidism. It may be the clinical manifestation of the disease or the adverse effect of antithyroid therapy. We report a 69-year-old male with hyperthyroidism who developed cholestasis and acute cholecystitis after a 4-day course of methimazole. After withdrawal of methimazole, his cholestasis subsided.

Key Words:  acute cholecystitis , cholestasis , hyperthyroidism , methimazole

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PII: S1873-9598(10)70009-0

doi:10.1016/S1873-9598(10)70009-0

International Journal of Gerontology
Volume 3, Issue 4 , Pages 248-250, December 2009

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