International Journal of Gerontology
Volume 3, Issue 3 , Pages 163-169 , September 2009

Clinical Genomics Identifies the Expression of Human Ovarian Carcinoma

  • Meng-Hsiun Tsai

      Affiliations

    • Department of Management Information Systems and Institute of Bioinformatics, National Chung Hsing University, Taichung, Taiwan
    • ,
  • Steve G. Huang

      Affiliations

    • Institute of Nanotechnology, National Chiao Tung University, Hsinchu, Taiwan
    • ,
  • Shyh-Chang Tsaur

      Affiliations

    • Department of Computer Science and Information Engineering, Asia University, Taichung, Taiwan
    • ,
  • Yao-Ching Hung

      Affiliations

    • Section of Gynecologic Oncology, Department of Obstetrics and Gynecology, China Medical University and Hospital, Taichung, Taiwan
    • ,
  • Sheng-Hsiung Chiu

      Affiliations

    • Troilus Bio-technology Co. Ltd, Taichung, Taiwan
    • ,
  • Chi-Wei Wang

      Affiliations

    • Department of Computer Science and Information Engineering, Asia University, Taichung, Taiwan
    • Department of Internal Medicine, Ben Tang Cheng Ching Hospital, Taichung, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Chi-Wei Wang, Department of Internal Medicine, Ben Tang Cheng Ching Hospital, 718, Zhongzheng Road, Wufeng Township, Taichung County 413, Taiwan

,Accepted 8 March 2009.

References 

  1. Jemal A , Thomas A , Murray T , et al.   Cancer statistics, 2002 . CA Cancer J Clin . 2002;52:23–47
  2. Yamamoto S , Konishi I , Mandai M , et al.   Expression of vascular endothelial growth factor (VEGF) in epithelial ovarian neoplasms: correlation with clinicopathology and patient survival, and analysis of serum VEGF levels . Br J Cancer . 1997;76:1221–1227
  3. Schena M , Shalon D , Davis RW , et al.   Quantitative monitoring of gene expression patterns with a complementary DNA microarray . Science . 1995;270:467–470
  4. Alizadeh AA , Eisen MB , Davis RE , et al.   Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling . Nature . 2000;403:503–511
  5. DeRisi J , Penland L , Brown PO , et al.   Use of a cDNA micro-array to analyse gene expression patterns in human cancer . Nat Genet . 1996;14:457–460
  6. Schummer M , Ng WV , Bumgarner RE , et al.   Comparative hybridization of an array of 21,500 ovarian cDNAs for the discovery of genes overexpressed in ovarian carcinomas . Gene . 1999;238:375–385
  7. Wang K , Gan L , Jeffery E , et al.   Monitoring gene expression profile changes in ovarian carcinomas using cDNA microarray . Gene . 1999;229:101–108
  8. Ismail RS , Baldwin RL , Fang J , et al.   Differential gene expression between normal and tumor-derived ovarian epithelial cells . Cancer Res . 2000;60:6744–6749
  9. Martoglio AM , Tom BD , Starkey M , et al.   Changes in tumorigenesis-and angiogenesis-related gene transcript abundance profiles in ovarian cancer detected by tailored high density cDNA arrays . Mol Med . 2000;6:750–765
  10. Ono K , Tanaka T , Tsunoda T , et al.   Identification by cDNA microarray of genes involved in ovarian carcinogenesis . Cancer Res . 2000;60:5007–5011
  11. Welsh JB , Zarrinkar PP , Sapinoso LM , et al.   Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer . Proc Natl Acad Sci USA . 2001;98:1176–1181
  12. Pecorelli S , Odicino F , Maisonneuve P , et al.   FIGO annual report on the results of treatment in gynaecological cancer: carcinoma of the ovary . J Epidemiol Biostat . 1998;3:75–102
  13. Brazma A , Hingamp P , Quackenbush J , et al.   Minimum information about a microarray experiment (MIAME)-toward standards for microarray data . Nat Genet . 2001;29:365–371
  14. Cleveland WS . Robust locally weighted regression and smoothing scatter plots . J Am Stat Assoc . 1979;74:829–836
  15. Neyns B , Katesuwanasing  , Vermeij J , et al.   Expression of the jun family of genes in human ovarian cancer and normal ovarian surface epithelium . Oncogene . 1996;12:1247–1257
  16. Morrison TB , Weis JJ , Wittwer CT . Quantification of lowcopy transcripts by continuous SYBR Green I monitoring during amplification . Biotechniques . 1998;24:954–962
  17. Heintz AP , Odicino F , Maisonneuve P , et al.   Carcinoma of the ovary . J Epidemiol Biostat . 2001;6:107–138
  18. Holmes D , Brynjolfsson J , Brett P , et al.   No evidence for a susceptibility locus predisposing to manic depression in the region of the dopamine (D2) receptor gene . Br J Psychiatry . 1991;158:635–641
  19. Boerboom D , Pilon N , Behdjani R , et al.   Expression and regulation of transcripts encoding two members of the NR5A nuclear receptor subfamily of orphan nuclear receptors, steroidogenic factor-1 and NR5A2, in equine ovarian cells during the ovulatory process . Endocrinology . 2000;141:4647–4656
  20. Laflamme C , Filion C , Bridge JA , et al.   The homeotic protein Six3 is a coactivator of the nuclear receptor NOR-1 and a corepressor of the fusion protein EWS/NOR-1 in human extraskeletal myxoid chondrosarcomas . Cancer Res . 2003;63:449–454
  21. Jenkins DC , Charles IG , Thomsen LL , et al.   Roles of nitric oxide in tumor growth . Proc Natl Acad Sci USA . 1995;92:4392–4396

PII: S1873-9598(09)70042-0

doi: 10.1016/S1873-9598(09)70042-0

International Journal of Gerontology
Volume 3, Issue 3 , Pages 163-169 , September 2009

Article Tools