Body Mass Index as a Predictor of Mortality in Older People in Taiwan
Article Outline
SUMMARY
Background
Obesity is associated with diverse health risks, but its role as a risk factor for death remains controversial in the elderly. This study estimated the association of body mass index (BMI) with the risk of death from any cause and from specific diseases in elderly Taiwanese.
Methods
The Six-Community Hypertension Intervention Project Study, a nationwide population-based cohort, was conducted in 1982 and followed up for 23 years. Cause of death was ascertained by review of death certificate files. Proportional hazards models were used to evaluate the association between the baseline BMI and risk of death.
Results
Of 1,568 participants aged 65 years (range, 60–75 years) at study entry, 1,085 (69%) died during follow-up. The relationship between death from any cause and BMI follows a J-shaped pattern. Increasing BMI categories were associated with increased risk of all-cause mortality (BMI, 25–26.9: hazard ratio, HR, 1.36; 95% confidence interval, CI, 1.11–1.67; BMI ≥ 27: HR, 1.46; 95% CI, 1.15–1.85). Death from diabetes, cardiovascular diseases or cancer increased progressively with increasing categories of BMI, and HRs were significantly increased at BMI levels > 23.0kg/m2 (BMI, 23–24.9: HR, 1.29; 95% CI, 1.05–1.60; BMI, 25–26.9: HR, 1.58; 95% CI, 1.21–2.05; BMI ≥ 27: HR, 1.74; 95% CI, 1.29–2.35). These associations were more obvious in men than in women.
Conclusion
This study found that BMI > 25kg/m2 was a significant independent predictor of all-cause mortality, especially among older men. BMI > 23kg/m2 also increased risk of mortality from cancer, cardiovascular diseases and diabetes. The relationship was J-shaped in older Taiwanese.
Key Words: body mass index , elderly , mortality , obesity , Taiwan
No full text is available. To read the body of this article, please view the PDF online.
References
- Prevalence of overweight and obesity and its associated factors: findings from National Nutrition and Health Survey in Taiwan, 1993-1996 . Prev Med . 2003;37:233–241
- . Prevalence of obesity and metabolic syndrome in Taiwan . J Formos Med Assoc . 2006;105:626–635
- Body weight and mortality among women . N Engl J Med . 1995;333:677–685
- . Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults . N Engl J Med . 2003;348:1625–1638
- . Body-mass index and mortality in a prospective cohort of U.S. adults . N Engl J Med . 1999;341:1097–1105
- . Excess deaths associated with underweight, overweight, and obesity . JAMA . 2005;293:1861–1867
- . The effect of age on the association between body-mass index and mortality . N Engl J Med . 1998;338:1–7
- . Hazard of obesity-the Norwegian experience . Acta Med Scand Suppl . 1988;723:17–21
- . Impact of age on associations between weight and mortality . Nutr Rev . 2000;58:129–137
- . Weight and mortality in Finnish men . J Clin Epidemiol . 1989;42:781–789
- . Body mass index and patterns of mortality among Seventh-day Adventist men . Int J Obes . 1991;15:397–406
- . Anthropometric measurements as predictors of mortality in a community population aged 70 years and over . Age Ageing . 1990;19:131–135
- . Body weight as a risk factor in the elderly . Arch Intern Med . 1990;150:1065–1072
- . An evidence-based assessment of federal guidelines for overweight and obesity as they apply to elderly persons . Arch Intern Med . 2001;161:1194–1203
- . Elevated body mass index and mortality risk in the elderly . Obes Rev . 2007;8:41–59
- . A nested case control study on multiple risk factors for acute fatal cerebrovas-cular accident and coronary heart disease . Chin J Fam Med . 1997;7:121–130
- . Criteria and classification of obesity in Japan and Asia-Oceania . Asia Pac J Clin Nutr . 2002;11(Suppl 8):S732–S737
- . Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults-the evidence report . Obes Res . 1998;6(Suppl 2):S51–209
- . Body weight: implications for the prevention of coronary heart disease, stroke, and diabetes mellitus in a cohort study of middle aged men . BMJ . 1997;314:1311–1317
- Body mass index and nine-year mortality in disabled and nondisabled older U.S. individuals . J Am Geriatr Soc . 2008;56:105–110
- . Association of body mass index and weight change with all-cause mortality in the elderly . Am J Epidemiol . 2006;163:938–949
- Obesity, physical activity, and mortality in a prospective Chinese elderly cohort . Arch Intern Med . 2006;166:1498–1504
- . The association of body weight and anthropometry with mortality in elderly men: the Honolulu Heart Program . Int J Obes Relat Metab Disord . 1999;23:395–402
- . Physical inactivity, excess adiposity and premature mortality . Obes Rev . 2003;4:257–290
- Body-mass index and mortality in Korean men and women . N Engl J Med . 2006;355:779–787
- . A prospective study of adiposity and all-cause mortality: the Malmo Diet and Cancer Study . Obes Res . 2002;10:361–369
- Does weight loss from middle age to old age explain the inverse weight mortality relation in old age? . Am J Epidemiol . 1995;141:312–321
- . How useful is body mass index for comparison of body fatness across age, sex, and ethnic groups? . Am J Epidemiol . 1996;143:228–239
- . Mortality associated with body fat, fat-free mass and body mass index among 60-year-old Swedish men-a 22-year follow-up. The study of men born in 1913 . Int J Obes Relat Metab Disord . 2000;24:33–37
PII: S1873-9598(09)70019-5
doi:10.1016/S1873-9598(09)70019-5
© 2009 Elsevier B.V. All rights reserved.
