International Journal of Gerontology
Volume 1, Issue 3 , Pages 118-124 , September 2007

Botulism: A Frequently Forgotten Old Malady

  • Teguh Thajeb

      Affiliations

    • Department of Internal Medicine, Chang-Gung Memorial Hospital, Lin-Kou, Taipei, Taiwan
    • Department of Internal Medicine, Li-Shin Hospital, Ping-Jen City, Taoyuan, Taipei, Taiwan
  • ,
  • Yi-Min Chen

      Affiliations

    • Department of Neurology and Medical Research, Mackay Memorial Hospital, Taipei, Taiwan
  • ,
  • Dao-Fu Dai

      Affiliations

    • Department of Pathology, School of Medicine, University of Washington, Seattle, USA
  • ,
  • Daniel Daile Thajeb

      Affiliations

    • School of Biotechnology, Asia University, Taichung, Taipei, Taiwan
  • ,
  • Peterus Thajeb

      Affiliations

    • Department of Neurology and Medical Research, Mackay Memorial Hospital, Taipei, Taiwan
    • School of Medicine, National Yang-Ming University, Taipei, Taiwan
    • School of Medicine, Taipei Medical University, Taipei, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Peterus Thajeb, School of Medicine, National Yang-Ming University, P.O. Box Nei-Hu 6-30, Taipei City 11499, Taiwan

,Accepted 15 March 2007.

References 

  1. van Ermengem E . Classics in infectious diseases. A new anaerobic bacillus and its relation to botulism. [Originally published as “Ueber einen neuen anaëroben Bacillus und seine Beziehungen zum Botulismus” in Zeitschrift für Hygiene und Infektionskrankheiten 26: 1-56, 1897.] . Rev Infect Dis . 1979;1:701–719
  2. Griffin JW . Bacterial toxins: botulism and tetanus . In:  Kennedy PGE ,  Johnson RT editor. Infections of the Nervous System . London: Butterworth; 1987;p. 76–92
  3. Hatheway CL . Botulism: the present status of the disease . Curr Top Microbiol Immunol . 1995;195:55–75
  4. Mayer RF . The neuromuscular defect in human botulism . In:  Locke S editors. Modern Neurology . Boston: Little Brown; 1969;p. 169–186
  5. Ropper AH , Brown RH . In: Adams and Victor's Principles of Neurology . 8th edition. New York: McGraw-Hill; 2005;p. 1032
  6. Sakaguchi G , Oishi I , Kozaki S , Sakaguchi S , Kitamura M . Molecular structures and biological activities of Clostridium botulinum toxins . Jpn J Med Sci Biol . 1974;27:95–99
  7. Simpson LL , Rapport MM . Ganglioside inactivation of botulinum toxin . J Neurochem . 1971;18:1341–1343
  8. Lamanna C , Sakaguchi G . Botulinal toxins and the problem of nomenclature of simple toxins . Bacteriol Rev . 1971;35:242–249
  9. Ivanova LG . [The hemagglutinin of Clostridium botulinum. Extraction, chemical characteristics and serologic specificity.] Zh Mikrobiol Epidemiol Immunobiol 1975;10:14-8. [In Russian] 10. DasGupta BR, Sugiyama H. Comparative sizes of type A and B botulinum neurotoxins . Toxicon . 1977;15:357–363
  10. Syuto B , Kubo S . Structure and toxicity of Clostridium botulinum type C toxin . Jpn J Med Sci Biol . 1979;32:132–133
  11. Howard BD , Gundersen CB . Effects and mechanisms of polypeptide neurotoxins that act presynaptically . Annu Rev Pharmacol Toxicol . 1980;20:307–336
  12. Simpson LL . The origin, structure, and pharmacological activity of botulinum toxin . Pharmacol Rev . 1981;33:155–188
  13. DasGupta BR , Rasmussen S . Purification and amino acid composition of type E botulinum neurotoxin . Toxicon . 1983;21:535–545
  14. DasGupta BR , Rasmussen S . Amino acid composition of Clostridium botulinum type F neurotoxin . Toxicon . 1983;21:566–569
  15. DasGupta BR , Woody MA . Amino acid composition of Clostridium botulinum type B neurotoxin . Toxicon . 1984;22:312–315
  16. DasGupta BR , Sathyamoorthy V . Purification and amino acid composition of type A botulinum neurotoxin . Toxicon . 1984;22:415–424
  17. Smith GR , Milligan RA . Clostridium botulinum type D in Britain . Vet Rec . 1977;100:121–122
  18. Simpson LL . Studies on the mechanism of action of botulinum toxin . Adv Cytopharmacol . 1979;3:27–34
  19. Swaminathan S , Eswaramoorthy S , Kumaran D . Structure and enzymatic activity of botulinum neurotoxins . Mov Disord . 2004;19(Suppl 8):S17–S22
  20. Hicks RP , Hartell MG , Nichols DA , Bhattacharjee AK , van Hamont JE , Skillman DR . The medicinal chemistry of botulinum, ricin and anthrax toxins . Curr Med Chem . 2005;12:667–690
  21. Sugii S , Ohishi I , Sakaguchi G . Correlation between oral toxicity and in vitro stability of Clostridium botulinum type A and B toxins of different molecular sizes . Infect Immun . 1977;16:910–914
  22. Sellin LC . The action of botulinum toxin at the neuromuscular junction . Med Biol . 1981;59:11–20
  23. Cull-Candy SG , Lundh H , Thesleff S . Effects of botulinum toxin on neuromuscular transmission in the rat . J Physiol . 1976;260:177–203
  24. Simpson LL . Kinetic studies on the interaction between botulinum toxin type A and the cholinergic neuromuscular junction . J Pharmacol Exp Ther . 1980;212:16–21
  25. Swift TR . Disorders of neuromuscular transmission other than myasthenia gravis . Muscle Nerve . 1981;4:334–353
  26. Otofuji T , Tokiwa H , Takahashi K . A food-poisoning incident caused by Clostridium botulinum toxin A in Japan . Epidemiol Infect . 1987;99:167–172
  27. Arnon SS , Midura TF , Clay SA , Wood RM , Chin J . Infant botulism. Epidemiological, clinical, and laboratory aspects . JAMA . 1977;237:1946–1951
  28. Sonnabend OA , Sonnabend WF , Krech U , Molz G , Sigrist T . Continuous microbiological and pathological study of 70 sudden and unexpected infant deaths: toxigenic intestinal Clostridium botulinum infection in 9 cases of sudden infant death syndrome . Lancet . 1985;325:237–241
  29. Sonnabend O , Sonnabend W , Heinzle R , Sigrist T , Dirnhofer R , Krech U . Isolation of Clostridium botulinum type G and identification of type G botulinal toxin in humans: report of five sudden unexpected deaths . J Infect Dis . 1981;143:22–27
  30. Shih Y , Chao SY . Botulism in China . Rev Infect Dis . 1986;8:984–990
  31. Tsai CC , Ting SC . Ecological studies of Clostridium botulinum in soils of Taiwan . J Formos Med Assoc . 1977;76:563–570
  32. Hatheway CL , McCroskey LM . Examination of feces and serum for diagnosis of infant botulism in 336 patients . J Clin Microbiol . 1987;25:2334–2338
  33. Hauschild AH , Gauvreau L . Food-borne botulism in Canada, 1971-1984 . CMAJ . 1985;133:1141–1146
  34. Rouhbakhsh-Khaleghdoust A , Pourtaghva M . A large outbreak of type E botulism in Iran . Trans R Soc Trop Med Hyg . 1977;71:444
  35. O'Mahony M , Mitchell E , Gilbert RJ , Hutchinson DN , Begg NT , Rodhouse JC , et al.   An outbreak of foodborne botulism associated with contaminated hazelnut yoghurt . Epidemiol Infect . 1990;104:389–395
  36. Horwitz MA , Hughes JM , Merson MH , Gangarosa EJ . Food-borne botulism in the United States, 1970-1975 . J Infect Dis . 1977;136:153–159
  37. Oh SJ . Botulism: electrophysiological studies . Ann Neurol . 1977;1:481–485
  38. Pickett JB . Botulism: AAEE case report 16 . Muscle Nerve . 1988;11:1201–1205
  39. Sonnabend WF , Sonnabend OA , Grundler P , Ketz E . Intestinal toxicoinfection by Clostridium botulinum type F in an adult. Case associated with Guillain-Barré syndrome . Lancet . 1987;329:357–361
  40. Tsujihata M , Kinoshita I , Mori M , Mori K , Shirabe S , Satoh A , et al.   Ultrastructural study of the motor endplate in botulism and Lambert-Eaton myasthenic syndrome . J Neurol Sci . 1987;81:197–213
  41. Vita G , Girlanda P , Puglisi RM , Marabello L , Messina C . Cardiovascular reflex testing and single-fiber electromyography in botulism. A longitudinal study . Arch Neurol . 1987;44:202–206
  42. Wilcox PG , Morrison NJ , Pardy RL . Recovery of the ventilatory and upper airway muscles and exercise performance after type A botulism . Chest . 1990;98:620–626

PII: S1873-9598(08)70032-2

doi: 10.1016/S1873-9598(08)70032-2

International Journal of Gerontology
Volume 1, Issue 3 , Pages 118-124 , September 2007