International Journal of Gerontology
Volume 2, Issue 2 , Pages 60-66, June 2008

Outcome of Non-Traumatic Out-of-hospital Cardiac Arrest in the Elderly

  • Ding-Kuo Chien

      Affiliations

    • Department of Emergency Medicine, Mackay Memorial Hospital, Taipei, Taiwan
    • Mackay Medicine, Nursing and Management College, Taipei, Taiwan
    • Graduate Institute of Injury Prevention and Control, Taipei Medical University, Taipei, Taiwan
  • ,
  • Wen-Han Chang

      Affiliations

    • Department of Emergency Medicine, Mackay Memorial Hospital, Taipei, Taiwan
    • Corresponding Author InformationCorrespondence to: Dr Wen-Han Chang, Department of Emergency Medicine, Mackay Memorial Hospital, 92, Section 2, Chungshan North Road, Taipei, Taiwan
  • ,
  • Shin-Han Tsai

      Affiliations

    • Graduate Institute of Injury Prevention and Control, Taipei Medical University, Taipei, Taiwan
  • ,
  • Kuo-Song Chang

      Affiliations

    • Department of Emergency Medicine, Mackay Memorial Hospital, Taipei, Taiwan
  • ,
  • Chang-Chih Chen

      Affiliations

    • Department of Emergency Medicine, Mackay Memorial Hospital, Taipei, Taiwan
    • School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan
  • ,
  • Yu-Jang Su

      Affiliations

    • Department of Emergency Medicine, Mackay Memorial Hospital, Taipei, Taiwan
    • Mackay Medicine, Nursing and Management College, Taipei, Taiwan

Accepted 15 February 2008.

Article Outline

Summary 

Background

Because of changes in lifestyle and the advancement of medical science, human life expectancy in Taiwan is longer than it used to be. Since 1993, we have had an “aging population”, i.e., the proportion of the elderly population is greater than 7% of the general population and is increasing over time. However, to our knowledge, no study of the outcomes of out-of-hospital cardiac arrest (OHCA) in the elderly has been performed in Taiwan. This study was, therefore, undertaken to identify both the outcomes of these occurrences and the factors that influenced them.

Methods

This was a retrospective study. The characteristics of 299 nontraumatic OHCA patients (elderly/adult ratio, 198:101), who received cardiopulmonary resuscitation upon arrival at the emergency department (ED) between January 1, 2005 and December 31, 2005 were reviewed. The group was split between “elderly patients” aged 65 or over and “adult patients” aged 18 to 64. The outcome measurements included return of spontaneous circulation (ROSC) at the ED, survival to hospital admission, and survival to hospital discharge with full neurologic function.

Results

The overall survival rate of patients was 7.4%. Of the 198 elderly patients, 85 (42.9%) had ROSC, 50 (25.3%) survived to admission and 12 (6.1%) survived to hospital discharge. In comparison, of the 101 adult patients, 32 (31.7%) had ROSC, 21 (20.8%) survived to admission and 10 (9.9%) survived to hospital discharge. The differences in outcomes between the two groups were not statistically significant. In the subgroup of patients who had ROSC at the ED, the adult group had a higher rate of survival to hospital discharge than the elderly (31.3% vs. 14.1%; p = 0.035); but in multivariate analysis, only the initial ventricular fibrillation/ventricular tachycardia rhythm predicted survival rate (odds ratio, 7.912; p = 0.007). The factor that predicted ROSC was witnessed arrest. Factors that predicted hospital discharge included witnessed arrest and shorter duration of resuscitation in the ED. Post-resuscitation neurologic outcomes of the survivors showed no significant difference between the two groups.

Conclusion

It is rational and necessary to aggressively resuscitate in cases of cardiac arrest among the elderly, because their age did not significantly decrease their survival rate or worsen their post-resuscitation neurologic outcomes, compared with non-elderly patients. All the elderly survivors studied were witnessed arrest cases, with return of circulation within 20 minutes at the ED.

Key Words:  elderly , out-of-hospital cardiac arrest , resuscitation , survival rate

No full text is available. To read the body of this article, please view the PDF online.

 

Back to Article Outline

References 

  1. Population Projections for Taiwan Area 2006–2051 Report. Council for Economic Planning and Development, Executive Yuan, Taiwan, Republic of China, June, 2005.
  2. Cummins RO , Ornato JP , Thies WH , Pepe PE . Improving survival from sudden cardiac arrest: the “chain of survival” concept. A statement for health professionals from the Advanced Cardiac Life Support Subcommittee and the Emergency Cardiac Care Committee, American Heart Association . Circulation . 1991;83:1832–1847
  3. Cooper JA , Cooper JD , Cooper JM . Cardiopulmonary resuscitation: history, current practice, and future direction . Circulation . 2006;114:2839–2849
  4. Hu SC . Out-of-hospital cardiac arrest in an Oriental metropolitan city . Am J Emerg Med . 1994;12:491–494
  5. Chang MY , Lin M , Kuo HW . Outcome of out-of-hospital cardiac arrest in southern Taiwan: a multivariate analysis . Acta Cardiol Sin . 2001;17:29–36
  6. Lin JN , Lin TJ , Kuo MC , Chou JJ , Lin CK , Tsai MS . Analysis of factors associated with successful cardiopulmonary resuscitation in non-traumatic dead-on-arrival patients in emergency department . Kaohsiung J Med Sci . 2002;18:84–90
  7. Chang MY , Lin M . Predictors of survival and hospital outcome of prehospital cardiac arrest in southern Taiwan . J Formos Med Assoc . 2005;104:639–646
  8. Herlitz J , Eek M , Engdahl J , Holmberg M , Holmberg S . Factors at resuscitation and outcome among patients suffering from out of hospital cardiac arrest in relation to age . Resuscitation . 2003;58:309–317
  9. Taffet GE , Teasdale TA , Luchi RJ . In-hospital cardiopulmonary resuscitation . JAMA . 1988;260:2069–2072
  10. Tresch DD , Thakur R , Hoffmann RG , Brooks HL . Comparison of outcome of resuscitation of out-of-hospital cardiac arrest in persons younger and older than 70 years of age . Am J Cardiol . 1988;61:1120–1122
  11. Gulati RS , Bhan GL , Horan MA . Cardiopulmonary resuscitation of old people . Lancet . 1983;2:267–269
  12. Juchems R , Wahlig G , Frese W . Influence of age on the survival rate of out-of-hospital and in-hospital resuscitation . Resuscitation . 1993;26:23–29
  13. Khalafi K , Ravakhah K , West BC . Avoiding the futility of resuscitation . Resuscitation . 2001;50:161–166
  14. Linn BS , Yurt RW . Cardiac arrest among geriatric patients . Br Med J . 1970;2:25–27
  15. Longstreth WT , Cobb LA , Fahrenbruch CE , Copass MK . Does age affect outcomes of out-of-hospital cardiopulmonary resuscitation? . JAMA . 1990;264:2109–2110
  16. Van Hoeyweghen RJ , Bossaert LL , Mullie A , Martens P , Delooz HH , Buylaert WA , et al.   Survival after out-ofhospital cardiac arrest in elderly patients. Belgian Cerebral Resuscitation Study Group . Ann Emerg Med . 1992;21:1179–1184
  17. Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. The American Heart Association in collaboration with the International Liaison Committee on Resuscitation (ILCOR) . Circulation . 2000;102(8 Suppl):I90–I94
  18. Cummins RO , Chamberlain DA , Abramson NS , Allen M , Baskett PJ , Becker L , et al.   Recommended guidelines for uniform reporting of data from out-of-hospital cardiac arrest: the Utstein Style. A statement for health professionals from a task force of the American Heart Association, the European Resuscitation Council, the Heart and Stroke Foundation of Canada, and the Australian Resuscitation Council . Circulation . 1991;84:960–975
  19. Rogove HJ , Safar P , Sutton-Tyrrell K , Abramson NS . Old age does not negate good cerebral outcome after cardiopulmonary resuscitation: analyses from the brain resuscitation clinical trials. The Brain Resuscitation Clinical Trial I and II Study Groups . Crit Care Med . 1995;23:18–25
  20. Bonnin MJ , Pepe PE , Clark PS . Survival in the elderly after out-of-hospital cardiac arrest . Crit Care Med . 1993;21:1645–1651
  21. Murphy DJ , Murray AM , Robinson BE , Campion EW . Outcomes of cardiopulmonary resuscitation in the elderly . Ann Intern Med . 1989;111:199–205
  22. Swor RA , Jackson RE , Tintinalli JE , Pirrallo RG . Does advanced age matter in outcomes after out-of-hospital cardiac arrest in community-dwelling adults? . Acad Emerg Med . 2000;7:762–768
  23. Bonnin MJ , Pepe PE , Kimball KT , Clark PS . Distinct criteria for termination of resuscitation in the out-of-hospital setting . JAMA . 1993;270:1457–1462
  24. Tresch DD , Thakur RK , Hoffmann RG , Olson D , Brooks HL . Should the elderly be resuscitated following out-of-hospital cardiac arrest? . Am J Med . 1989;86:145–150
  25. Lapostolle F , Le Toumelin P , Agostinucci JM , Catineau J , Adnet F . Basic cardiac life support providers checking the carotid pulse: performance, degree of conviction, and influencing factors . Acad Emerg Med . 2004;11:878–880

PII: S1873-9598(08)70012-7

doi:10.1016/S1873-9598(08)70012-7

International Journal of Gerontology
Volume 2, Issue 2 , Pages 60-66, June 2008